2-ThiophenecarboxaMide, 5-chloro-N,N-diMethyl- - Names and Identifiers
2-ThiophenecarboxaMide, 5-chloro-N,N-diMethyl- - Physico-chemical Properties
2-ThiophenecarboxaMide, 5-chloro-N,N-diMethyl- - Introduction
2-ThiophenecarboxaMide, 5-chloro-N,N-diMethyl-(2-ThiophenecarboxaMide, 5-chloro-N,N-diMethyl-) is a pharmaceutical impurity with the chemical formula C8H9ClNOS and a molecular weight of 197.68g/mol. The following is a description of the properties, uses, preparation and safety information of the compound:
1. Nature:
2-ThiophenecarboxaMide, 5-chloro-N,N-diMethyl-is a white solid that is stable at room temperature. It has a strong odor and is soluble in organic solvents such as alcohol, ether and chloroform, but hardly soluble in water. This compound has a boiling point of 260-265°C and a melting point of 49-51°C.
2. Use:
2-ThiophenecarboxaMide, 5-chloro-N,N-diMethyl-is commonly used as a reference substance in the quality control of rivaroxaban drugs, and is used to analyze and detect the purity and content of rivaroxaban drugs.
3. Preparation method:
The preparation method of 2-ThiophenecarboxaMide, 5-chloro-N,N-diMethyl-is more complicated and usually requires multiple reactions. One of the possible preparation methods is the condensation reaction of 2-mercaptobenzoyl chloride with 5-chloro-2-carbamic acid tert-butyl ester, and the corresponding treatment and purification steps to obtain 2-ThiophenecarboxaMide, 5-chloro-N,N-diMethyl-.
4. Safety Information:
The specific safety information of 2-ThiophenecarboxaMide, 5-chloro-N,N-diMethyl-depends on its use and handling. As a chemical, it should be stored in a cool, dry place and away from fire and oxidants. Wear appropriate protective equipment during handling and operation to avoid contact with skin and eyes. If accidental contact occurs, immediately flush the affected area with plenty of water and seek medical help.
Please note that the information provided above is for reference only. When using and handling chemicals, it is recommended to always follow correct operating procedures and safety measures, and carefully read and follow the safety data sheets and instructions of the relevant products.
Last Update:2024-04-09 15:18:02